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Active Ingredients: Clopidol and Methyl Benzoquate
Specification:
-Appearance: White or off-white granular, odorless
- Clopidol content: 12.5%
- Methyl Benzoquate content: 1.67%

Active Ingredients: Clopidol and Methyl Benzoquate

Specification:

-Appearance: White or off-white granular, odorless

- Clopidol content: 12.5%

- Methyl Benzoquate content: 1.67%

 

Pharmacology:

1. Clopidol: Acts on the first day of the coccidia life cycle (sporozoite stage), inhibiting the development of the first-generation schizonts and reducing oocyst shedding; most effective against Eimeria tenella.

2. Methyl Benzoquate: Interferes with DNA synthesis during the early asexual reproduction stage of coccidia. Highly effective against 8 species of Eimeria, especially superior to clopidol alone against Eimeria necatrix, Eimeria maxima, and Eimeria acervulina.

3. Combination: A ratio of 7.485:100 (Methyl Benzoquate to Clopidol) produces a synergistic effect. The dosage of clopidol can be reduced to 1/4 of the original amount while maintaining high efficacy and significantly delaying drug resistance.

 

Indications:

For the prevention of coccidiosis in poultry (broilers, replacement pullets, breeding chickens, turkeys, quails), suitable for infections caused by sensitive and mildly resistant strains.

 

Usage& Dosage:

mixed feeding:

- Prevention: Add 500–650 g of this product per ton of feed.

- Severe: Add 750 g of this product per ton of feed.

 

Adverse Reactions:

No obvious adverse reactions at recommended doses. Overdosing (>2×) or long-term use (>14 days) may cause slight growth inhibition and soft feces, which recover after withdrawal.

 

Precautions:

1. Do not use in laying hens during egg production; withdrawal period for broilers is 5 days.

2. Do not mix with nicarbazin, sulfaquinoxaline, or amprolium to avoid antagonism.

3. Must be diluted stepwise (10-fold dilution method) to ensure uniformity (CV ≤5%).

4. Contraindicated in animals allergic to quinoline or pyridine drugs.

5. Operators should wear masks and gloves to avoid inhaling dust.

6. Store in a cool, dry place (≤25°C), sealed; use within 1 month after opening.

 

Withdrawal Period:

- Broilers: 5 days.  

- Laying hens: Not allowed during egg production.  

- Breeding chickens: Eggs must not be set for hatching within 3 days after withdrawal.

 

Packaging: 25 kg / bag

 

Storage: Store in a cool and dry place, in sealed or closed container.

 

Shelf Life: Two years.

CLOPIDOL PLUS (Clopidol 12.5%+Methyl Benzoquate 1.67% Granular)